Galore International Journal of Applied Sciences and Humanities

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Original Research Article

Year: 2018 | Month: July-September | Volume: 2 | Issue: 3 | Pages: 1-4

Heavy Metal Induced Alterations in Haematological Parameters of Rat


Visiting Faculty, Dr. G L Gupta Institute of Public Health, Lucknow University, New Campus, Lucknow


Oral exposure of lead acetate (100µg and 250µg /kg body weight) to rats for 30 and 90 days produced anaemia as evidenced by decrease in erythrocyte count, haemoglobin concentration and haematocrit values. However, exposure to lead resulted in elevation of white blood cell count. The increase in the number of neutrophils and lymphocytes may be a form of defensive process against the toxic effect of lead toxicity. The study suggests that the concentration of lead, which is highly toxic should be carefully controlled.

Key words: Chronic exposure, Lead acetate, Haematological parameters

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